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PIP5KI gamma Rabbit pAb

Cat No.: DPA04405
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Product Name: PIP5KI gamma Rabbit pAb
Cat No.: DPA04405
Clonality: Polyclonal
Species Reactivity: Human, Mouse, Rat
Tested Applications: WB,IP
Recommended Dilution: WB: 1:1000-1:5000
IP: 1:20-1:50
Size: 30ul 50ul 100uL
Format: Liquid
Source: Rabbit
Purification Method: Affinity Purification
Isotype: IgG
Conjugate: Un-conjugated
Storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a
Immunogen: Recombinant protein of mouse PIP5KI gamma
Calculated Molecular Weight: 73 kDa
Observed Molecular Weight: 90,87 kDa
GenBank Accession Number: O70161
Gene ID (NCBI): 18717
Synonyms: AI115456; AI835305; Pip5kIgamma
Background: Catalyzes the phosphorylation of phosphatidylinositol 4-phosphate (PtdIns4P) to form phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2). PtdIns(4,5)P2 is involved in a variety of cellular processes and is the substrate to form phosphatidylinositol 3,4,5-trisphosphate (PtdIns(3,4,5)P3), another second messenger. The majority of PtdIns(4,5)P2 is thought to occur via type I phosphatidylinositol 4-phosphate 5-kinases given the abundance of PtdIns4P. Participates in a variety of cellular processes such as vesicle mediated transport, cell adhesion, cell polarization and cell migration. Together with PIP5K1A is required for phagocytosis, but they regulate different types of actin remodeling at sequential steps.
Category: Primary Ab
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