PIP5KI gamma Rabbit pAb
Cat#:DPA04405应用:WB,IP
Product Name: | PIP5KI gamma Rabbit pAb |
Cat No.: | DPA04405 |
Clonality: | Polyclonal |
Species Reactivity: | Human, Mouse, Rat |
Tested Applications: | WB,IP |
Recommended Dilution: | WB: 1:1000-1:5000 IP: 1:20-1:50 |
Size: | 30ul 50ul 100uL |
Format: | Liquid |
Source: | Rabbit |
Purification Method: | Affinity Purification |
Isotype: | IgG |
Conjugate: | Un-conjugated |
Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
Immunogen: | Recombinant protein of mouse PIP5KI gamma |
Calculated Molecular Weight: | 73 kDa |
Observed Molecular Weight: | 90,87 kDa |
GenBank Accession Number: | O70161 |
Gene ID (NCBI): | 18717 |
Synonyms: | AI115456; AI835305; Pip5kIgamma |
Background: | Catalyzes the phosphorylation of phosphatidylinositol 4-phosphate (PtdIns4P) to form phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2). PtdIns(4,5)P2 is involved in a variety of cellular processes and is the substrate to form phosphatidylinositol 3,4,5-trisphosphate (PtdIns(3,4,5)P3), another second messenger. The majority of PtdIns(4,5)P2 is thought to occur via type I phosphatidylinositol 4-phosphate 5-kinases given the abundance of PtdIns4P. Participates in a variety of cellular processes such as vesicle mediated transport, cell adhesion, cell polarization and cell migration. Together with PIP5K1A is required for phagocytosis, but they regulate different types of actin remodeling at sequential steps. |
Category: | Primary Ab |