68kDa Neurofilament Rabbit pAb
Cat#:DPA03513应用:WB,FC,IP
Product Name: | 70 kD Neurofilament Light Rabbit pAb |
Cat No.: | DPA04406 |
Clonality: | Polyclonal |
Species Reactivity: | Human, Mouse, Rat |
Tested Applications: | WB,IP |
Recommended Dilution: | WB: 1:1000-1:2000 IP: 1:20 |
Size: | 30ul 50ul 100uL |
Format: | Liquid |
Source: | Rabbit |
Purification Method: | Affinity Purification |
Isotype: | IgG |
Conjugate: | Un-conjugated |
Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
Immunogen: | A synthetic peptide of human 70 kD Neurofilament Light |
Calculated Molecular Weight: | 62 kDa |
Observed Molecular Weight: | 70 kDa |
GenBank Accession Number: | P07196 |
Gene ID (NCBI): | 4747 |
Synonyms: | NFL; NF-L; NF68; CMT1F; CMT2E; PPP1R110 |
Background: | Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and they functionally maintain the neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the light chain neurofilament protein. Mutations in this gene cause Charcot-Marie-Tooth disease types 1F (CMT1F) and 2E (CMT2E), disorders of the peripheral nervous system that are characterized by distinct neuropathies. A pseudogene has been identified on chromosome Y. [provided by RefSeq, Oct 2008] |
Category: | Primary Ab |