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70 kD Neurofilament Light Rabbit pAb

Cat No.: DPA04406
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Product Name: 70 kD Neurofilament Light Rabbit pAb
Cat No.: DPA04406
Clonality: Polyclonal
Species Reactivity: Human, Mouse, Rat
Tested Applications: WB,IP
Recommended Dilution: WB: 1:1000-1:2000
IP: 1:20
Size: 30ul 50ul 100uL
Format: Liquid
Source: Rabbit
Purification Method: Affinity Purification
Isotype: IgG
Conjugate: Un-conjugated
Storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a
Immunogen: A synthetic peptide of human 70 kD Neurofilament Light
Calculated Molecular Weight: 62 kDa
Observed Molecular Weight: 70 kDa
GenBank Accession Number: P07196
Gene ID (NCBI): 4747
Synonyms: NFL; NF-L; NF68; CMT1F; CMT2E; PPP1R110
Background: Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and they functionally maintain the neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the light chain neurofilament protein. Mutations in this gene cause Charcot-Marie-Tooth disease types 1F (CMT1F) and 2E (CMT2E), disorders of the peripheral nervous system that are characterized by distinct neuropathies. A pseudogene has been identified on chromosome Y. [provided by RefSeq, Oct 2008]
Category: Primary Ab
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