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PDZK1 Rabbit pAb

Cat No.: DPA04473
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Product Name: PDZK1 Rabbit pAb
Cat No.: DPA04473
Clonality: Polyclonal
Species Reactivity: Human
Tested Applications: WB,IP
Recommended Dilution: WB: 1:1000-1:5000
IP: 1:20
Size: 30ul 50ul 100uL
Format: Liquid
Source: Rabbit
Purification Method: Affinity Purification
Isotype: IgG
Conjugate: Un-conjugated
Storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a
Immunogen: A synthetic peptide of human PDZK1
Calculated Molecular Weight: 57 kDa
Observed Molecular Weight: 70 kDa
GenBank Accession Number: Q5T2W1
Gene ID (NCBI): 5174
Synonyms: CAP70; CLAMP; PDZD1; NHERF3; NHERF-3
Background: This gene encodes a PDZ domain-containing scaffolding protein. PDZ domain-containing molecules bind to and mediate the subcellular localization of target proteins. The encoded protein mediates the localization of cell surface proteins and plays a critical role in cholesterol metabolism by regulating the HDL receptor, scavenger receptor class B type 1. Single nucleotide polymorphisms in this gene may be associated with metabolic syndrome, and overexpression of this gene may play a role in drug resistance of multiple myeloma. Pseudogenes of this gene are located on the long arm of chromosome 1. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2011]
Category: Primary Ab
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