Recombinant Histidyl tRNA Synthetase (HARS)
Cat#:TP02401应用:Positive Control; Immunogen; SDS-PAGE; WB
Product Name: | HARS Rabbit pAb |
Cat No.: | DPA04479 |
Clonality: | Polyclonal |
Species Reactivity: | Human |
Tested Applications: | WB,IHC,IP |
Recommended Dilution: | WB: 1:1000-1:5000 IHC: 1:20-1:50 IP: 1:20-1:50 |
Size: | 30ul 50ul 100uL |
Format: | Liquid |
Source: | Rabbit |
Purification Method: | Affinity Purification |
Isotype: | IgG |
Conjugate: | Un-conjugated |
Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
Immunogen: | A synthetic peptide of human HARS |
Calculated Molecular Weight: | 57 kDa |
Observed Molecular Weight: | 57 kDa |
GenBank Accession Number: | P12081 |
Gene ID (NCBI): | 3035 |
Synonyms: | HRS; CMT2W; USH3B |
Background: | Aminoacyl-tRNA synthetases are a class of enzymes that charge tRNAs with their cognate amino acids. The protein encoded by this gene is a cytoplasmic enzyme which belongs to the class II family of aminoacyl-tRNA synthetases. The enzyme is responsible for the synthesis of histidyl-transfer RNA, which is essential for the incorporation of histidine into proteins. The gene is located in a head-to-head orientation with HARSL on chromosome five, where the homologous genes share a bidirectional promoter. The gene product is a frequent target of autoantibodies in the human autoimmune disease polymyositis/dermatomyositis. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2012] |
Category: | Primary Ab |