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分子生物学
规格：
查看说明书pro Caspase-3 Rabbit pAb
Cat#:DPA01134应用：WB,IHC,ICC/IF,FC,IP
| Product Name: | Caspase-3 Rabbit pAb |
| Cat No.: | DPA04519 |
| Clonality: | Polyclonal |
| Species Reactivity: | Human |
| Tested Applications: | WB,IHC,ICC/IF,FC,IP |
| Recommended Dilution: | WB: 1:1000 IHC: 1:20 ICC/IF: 1:20 FC: 1:50 IP: 1:20 |
| Size: | 30ul 50ul 100uL |
| Format: | Liquid |
| Source: | Rabbit |
| Purification Method: | Affinity Purification |
| Isotype: | IgG |
| Conjugate: | Un-conjugated |
| Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
| Immunogen: | A synthetic peptide of human Caspase-3 |
| Calculated Molecular Weight: | 32 kDa |
| Observed Molecular Weight: | 32,17 kDa |
| GenBank Accession Number: | P42574 |
| Gene ID (NCBI): | 836 |
| Synonyms: | CPP32; SCA-1; CPP32B |
| Background: | The protein encoded by this gene is a cysteine-aspartic acid protease that plays a central role in the execution-phase of cell apoptosis. The encoded protein cleaves and inactivates poly(ADP-ribose) polymerase while it cleaves and activates sterol regulatory element binding proteins as well as caspases 6, 7, and 9. This protein itself is processed by caspases 8, 9, and 10. It is the predominant caspase involved in the cleavage of amyloid-beta 4A precursor protein, which is associated with neuronal death in Alzheimer's disease. [provided by RefSeq, Aug 2017] |
| Category: | Primary Ab |
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