CENPE Rabbit pAb
Cat#:DPA04530应用:WB
Product Name: | CENPE Rabbit pAb |
Cat No.: | DPA04530 |
Clonality: | Polyclonal |
Species Reactivity: | Human |
Tested Applications: | WB |
Recommended Dilution: | WB: 1:1000-1:5000 |
Size: | 30ul 50ul 100uL |
Format: | Liquid |
Source: | Rabbit |
Purification Method: | Affinity Purification |
Isotype: | IgG |
Conjugate: | Un-conjugated |
Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
Immunogen: | A synthetic peptide of human CENPE |
Calculated Molecular Weight: | 316 kDa |
Observed Molecular Weight: | 316 kDa |
GenBank Accession Number: | Q02224 |
Gene ID (NCBI): | 1062 |
Synonyms: | KIF10; CENP-E; MCPH13; PPP1R61 |
Background: | Centrosome-associated protein E (CENPE) is a kinesin-like motor protein that accumulates in the G2 phase of the cell cycle. Unlike other centrosome-associated proteins, it is not present during interphase and first appears at the centromere region of chromosomes during prometaphase. This protein is required for stable spindle microtubule capture at kinetochores which is a necessary step in chromosome alignment during prometaphase. This protein also couples chromosome position to microtubule depolymerizing activity. Alternative splicing results in multiple transcript variants encoding distinct protein isoforms. [provided by RefSeq, Nov 2014] |
Category: | Primary Ab |