蛋白
抗体
检测试剂盒
蛋白MARKER
分子生物学
规格：
查看说明书GLCNE Rabbit pAb
Cat#:DPA04581应用：WB,ICC/IF,IP
| Product Name: | GLCNE Rabbit pAb |
| Cat No.: | DPA04581 |
| Clonality: | Polyclonal |
| Species Reactivity: | Human, Rat |
| Tested Applications: | WB,ICC/IF,IP |
| Recommended Dilution: | WB: 1:1000-1:5000 ICC/IF: 1:50 IP: 1:20 |
| Size: | 30ul 50ul 100uL |
| Format: | Liquid |
| Source: | Rabbit |
| Purification Method: | Affinity Purification |
| Isotype: | IgG |
| Conjugate: | Un-conjugated |
| Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
| Immunogen: | A synthetic peptide of human GLCNE |
| Calculated Molecular Weight: | 79 kDa |
| Observed Molecular Weight: | 75 kDa |
| GenBank Accession Number: | Q9Y223 |
| Gene ID (NCBI): | 10020 |
| Synonyms: | NM; DMRV; IBM2; Uae1; GLCNE |
| Background: | The protein encoded by this gene is a bifunctional enzyme that initiates and regulates the biosynthesis of N-acetylneuraminic acid (NeuAc), a precursor of sialic acids. It is a rate-limiting enzyme in the sialic acid biosynthetic pathway. Sialic acid modification of cell surface molecules is crucial for their function in many biologic processes, including cell adhesion and signal transduction. Differential sialylation of cell surface molecules is also implicated in the tumorigenicity and metastatic behavior of malignant cells. Mutations in this gene are associated with sialuria, autosomal recessive inclusion body myopathy, and Nonaka myopathy. Alternative splicing of this gene results in transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008] |
| Category: | Primary Ab |
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