Recombinant CASP2 And RIPK1 Domain Containing Adaptor With Death Domain Protein (CRADD)
Cat#:TP01704应用:Positive Control; Immunogen; SDS-PAGE; WB
Product Name: | RAIDD Rabbit pAb |
Cat No.: | DPA04611 |
Clonality: | Polyclonal |
Species Reactivity: | Human, Rat |
Tested Applications: | WB,ICC/IF,FC,IP |
Recommended Dilution: | WB: 1:1000-1:2000 ICC/IF: 1:20-1:50 FC: 1:20 IP: 1:20 |
Size: | 30ul 50ul 100uL |
Format: | Liquid |
Source: | Rabbit |
Purification Method: | Affinity Purification |
Isotype: | IgG |
Conjugate: | Un-conjugated |
Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
Immunogen: | A synthetic peptide of human RAIDD |
Calculated Molecular Weight: | 23 kDa |
Observed Molecular Weight: | 23 kDa |
GenBank Accession Number: | P78560 |
Gene ID (NCBI): | 8738 |
Synonyms: | MRT34; RAIDD |
Background: | This gene encodes a protein containing a death domain (DD) motif. This protein recruits caspase 2/ICH1 to the cell death signal transduction complex, which includes tumor necrosis factor receptor 1 (TNFR1A) and RIPK1/RIP kinase, and acts in promoting apoptosis. A mutation in this gene was associated with cognitive disability. A related pseudogene is found on chromosome 3. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016] |
Category: | Primary Ab |