eIF3B Rabbit pAb
Cat#:DPA04676应用:WB,ICC/IF,FC,IP
Product Name: | eIF3B Rabbit pAb |
Cat No.: | DPA04681 |
Clonality: | Polyclonal |
Species Reactivity: | Human |
Tested Applications: | WB,IHC |
Recommended Dilution: | WB: 1:1000-1:5000 IHC: 1:20-1:50 |
Size: | 30ul 50ul 100uL |
Format: | Liquid |
Source: | Rabbit |
Purification Method: | Affinity Purification |
Isotype: | IgG |
Conjugate: | Un-conjugated |
Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
Immunogen: | A synthetic peptide of human eIF3B |
Calculated Molecular Weight: | 93 kDa |
Observed Molecular Weight: | 117 kDa |
GenBank Accession Number: | P55884 |
Gene ID (NCBI): | 8662 |
Synonyms: | PRT1; EIF3S9; EIF3-ETA; EIF3-P110; EIF3-P116 |
Background: | RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis (PubMed:9388245, PubMed:17581632, PubMed:25849773, PubMed:27462815). The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. |
Category: | Primary Ab |