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eIF3B Rabbit pAb

Cat No.: DPA04681
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Product Name: eIF3B Rabbit pAb
Cat No.: DPA04681
Clonality: Polyclonal
Species Reactivity: Human
Tested Applications: WB,IHC
Recommended Dilution: WB: 1:1000-1:5000
IHC: 1:20-1:50
Size: 30ul 50ul 100uL
Format: Liquid
Source: Rabbit
Purification Method: Affinity Purification
Isotype: IgG
Conjugate: Un-conjugated
Storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a
Immunogen: A synthetic peptide of human eIF3B
Calculated Molecular Weight: 93 kDa
Observed Molecular Weight: 117 kDa
GenBank Accession Number: P55884
Gene ID (NCBI): 8662
Synonyms: PRT1; EIF3S9; EIF3-ETA; EIF3-P110; EIF3-P116
Background: RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis (PubMed:9388245, PubMed:17581632, PubMed:25849773, PubMed:27462815). The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition.
Category: Primary Ab
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