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查看说明书Recombinant Human Nuclear Transcription Factor Y Subunit α/NFYA Protein
Cat#:TP05730应用：Positive Control; Immunogen; SDS-PAGE; WB
| Product Name: | NFYA Rabbit pAb |
| Cat No.: | DPA04718 |
| Clonality: | Polyclonal |
| Species Reactivity: | Human, Mouse, Rat |
| Tested Applications: | WB,ICC/IF,FC,IP |
| Recommended Dilution: | WB: 1:1000-1:5000 ICC/IF: 1:20-1:50 FC: 1:20 IP: 1:20-1:50 |
| Size: | 30ul 50ul 100uL |
| Format: | Liquid |
| Source: | Rabbit |
| Purification Method: | Affinity Purification |
| Isotype: | IgG |
| Conjugate: | Un-conjugated |
| Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
| Immunogen: | A synthetic peptide of human NFYA |
| Calculated Molecular Weight: | 37 kDa |
| Observed Molecular Weight: | 37 kDa |
| GenBank Accession Number: | P23511 |
| Gene ID (NCBI): | 4800 |
| Synonyms: | HAP2; CBF-A; CBF-B; NF-YA |
| Background: | The protein encoded by this gene is one subunit of a trimeric complex, forming a highly conserved transcription factor that binds to CCAAT motifs in the promoter regions in a variety of genes. Subunit A associates with a tight dimer composed of the B and C subunits, resulting in a trimer that binds to DNA with high specificity and affinity. The sequence specific interactions of the complex are made by the A subunit, suggesting a role as the regulatory subunit. In addition, there is evidence of post-transcriptional regulation in this gene product, either by protein degradation or control of translation. Further regulation is represented by alternative splicing in the glutamine-rich activation domain, with clear tissue-specific preferences for the two isoforms. [provided by RefSeq, Jul 2008] |
| Category: | Primary Ab |
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