Alpha-synuclein Rabbit pAb
Cat#:DPA03936应用:WB,IHC,IP
Product Name: | alpha/beta Synuclein Rabbit pAb |
Cat No.: | DPA05001 |
Clonality: | Polyclonal |
Species Reactivity: | Human, Mouse, Rat |
Tested Applications: | WB,ICC/IF,FC |
Recommended Dilution: | WB: 1:1000 ICC/IF: 1:20-1:100 FC: 1:20 |
Size: | 30ul 50ul 100uL |
Format: | Liquid |
Source: | Rabbit |
Purification Method: | Affinity Purification |
Isotype: | IgG |
Conjugate: | Un-conjugated |
Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
Immunogen: | A synthetic peptide of human alpha Synuclein |
Calculated Molecular Weight: | 14 kDa |
Observed Molecular Weight: | 18 kDa |
GenBank Accession Number: | P37840 |
Gene ID (NCBI): | 6622 |
Synonyms: | PD1; NACP; PARK1; PARK4 |
Background: | Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. Synucleins are abundantly expressed in the brain and alpha- and beta-synuclein inhibit phospholipase D2 selectively. SNCA may serve to integrate presynaptic signaling and membrane trafficking. Defects in SNCA have been implicated in the pathogenesis of Parkinson disease. SNCA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer's disease. Alternatively spliced transcripts encoding different isoforms have been identified for this gene. [provided by RefSeq, Feb 2016] |
Category: | Primary Ab |