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Phospho-Alpha-synuclein (Tyr125) Rabbit pAb

Cat No.: DPA05390
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Product Name: Phospho-Alpha-synuclein (Tyr125) Rabbit pAb
Cat No.: DPA05390
Clonality: Polyclonal
Species Reactivity: Human
Tested Applications: WB,ICC/IF
Recommended Dilution: WB: 1:1000
ICC/IF: 1:50
Size: 30ul 50ul 100uL
Format: Liquid
Source: Rabbit
Purification Method: Affinity Purification
Isotype: IgG
Conjugate: Un-conjugated
Storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a
Immunogen: A synthetic phosphopeptide corresponding to residues surrounding Tyr125 of human Alpha-synuclein
Calculated Molecular Weight: 14 kDa
Observed Molecular Weight: 16 kDa
GenBank Accession Number: P37840
Gene ID (NCBI): 6622
Synonyms: PD1; NACP; PARK1; PARK4
Background: Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. Synucleins are abundantly expressed in the brain and alpha- and beta-synuclein inhibit phospholipase D2 selectively. SNCA may serve to integrate presynaptic signaling and membrane trafficking. Defects in SNCA have been implicated in the pathogenesis of Parkinson disease. SNCA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer's disease. Alternatively spliced transcripts encoding different isoforms have been identified for this gene. [provided by RefSeq, Feb 2016]
Category: Primary Ab
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