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DNA Polymerase gamma Rabbit pAb

Cat No.: DPA05135
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Product Name: DNA Polymerase gamma Rabbit pAb
Cat No.: DPA05135
Clonality: Polyclonal
Species Reactivity: Human, Mouse, Rat
Tested Applications: WB
Recommended Dilution: WB: 1:1000-1:5000
Size: 30ul 50ul 100uL
Format: Liquid
Source: Rabbit
Purification Method: Affinity Purification
Isotype: IgG
Conjugate: Un-conjugated
Storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a
Immunogen: A synthetic peptide of human DNA Polymerase gamma
Calculated Molecular Weight: 140 kDa
Observed Molecular Weight: 140 kDa
GenBank Accession Number: P54098
Gene ID (NCBI): 5428
Synonyms: PEO; MDP1; SCAE; MIRAS; POLG1; POLGA; SANDO; MTDPS4A; MTDPS4B
Background: Mitochondrial DNA polymerase is heterotrimeric, consisting of a homodimer of accessory subunits plus a catalytic subunit. The protein encoded by this gene is the catalytic subunit of mitochondrial DNA polymerase. The encoded protein contains a polyglutamine tract near its N-terminus that may be polymorphic. Defects in this gene are a cause of progressive external ophthalmoplegia with mitochondrial DNA deletions 1 (PEOA1), sensory ataxic neuropathy dysarthria and ophthalmoparesis (SANDO), Alpers-Huttenlocher syndrome (AHS), and mitochondrial neurogastrointestinal encephalopathy syndrome (MNGIE). Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
Category: Primary Ab
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