Recombinant Human MDP1 Protein
Cat#:TP02936应用:Positive Control; Immunogen; SDS-PAGE; WB
Product Name: | POLG Recombinant Rabbit mAb |
Cat No.: | RMA02457 |
Clonality: | Monoclonal |
Species Reactivity: | Human |
Tested Applications: | WB |
Recommended Dilution: | WB |
Size: | 30ul 50ul 100uL |
Format: | Liquid |
Source: | Rabbit |
Purification Method: | Affinity Purification |
Isotype: | IgG |
Conjugate: | Un-conjugated |
Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
Immunogen: | A synthetic peptide of human POLG |
Calculated Molecular Weight: | 140 kDa |
Observed Molecular Weight: | 140 kDa |
GenBank Accession Number: | P54098 |
Gene ID (NCBI): | 5428 |
Synonyms: | PEO; MDP1; SCAE; MIRAS; POLG1; POLGA; SANDO; MTDPS4A; MTDPS4B |
Background: | Mitochondrial DNA polymerase is heterotrimeric, consisting of a homodimer of accessory subunits plus a catalytic subunit. The protein encoded by this gene is the catalytic subunit of mitochondrial DNA polymerase. The encoded protein contains a polyglutamine tract near its N-terminus that may be polymorphic. Defects in this gene are a cause of progressive external ophthalmoplegia with mitochondrial DNA deletions 1 (PEOA1), sensory ataxic neuropathy dysarthria and ophthalmoparesis (SANDO), Alpers-Huttenlocher syndrome (AHS), and mitochondrial neurogastrointestinal encephalopathy syndrome (MNGIE). Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008] |
Category: | Primary Ab |