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eIF4EBP1 Rabbit pAb

Cat No.: DPA05175
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Product Name: eIF4EBP1 Rabbit pAb
Cat No.: DPA05175
Clonality: Polyclonal
Species Reactivity: Human
Tested Applications: WB,IHC,FC,IP
Recommended Dilution: WB: 1:1000
IHC: 1:20
FC: 1:20
IP: 1:20
Size: 30ul 50ul 100uL
Format: Liquid
Source: Rabbit
Purification Method: Affinity Purification
Isotype: IgG
Conjugate: Un-conjugated
Storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a
Immunogen: A synthetic peptide of human eIF4EBP1
Calculated Molecular Weight: 12 kDa
Observed Molecular Weight: 15-20 kDa
GenBank Accession Number: Q13541
Gene ID (NCBI): 1978
Synonyms: BP-1; 4EBP1; 4E-BP1; PHAS-I
Background: This gene encodes one member of a family of translation repressor proteins. The protein directly interacts with eukaryotic translation initiation factor 4E (eIF4E), which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5' end of mRNAs. Interaction of this protein with eIF4E inhibits complex assembly and represses translation. This protein is phosphorylated in response to various signals including UV irradiation and insulin signaling, resulting in its dissociation from eIF4E and activation of mRNA translation. [provided by RefSeq, Jul 2008]
Category: Primary Ab
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