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分子生物学
规格：
查看说明书eIF4EBP1 Rabbit pAb
Cat#:DPA01233应用：WB,IHC,ICC/IF,FC,IP
| Product Name: | Phospho-eIF4EBP1/eIF4EBP2/eIF4EBP3 (Thr45) Rabbit pAb |
| Cat No.: | DPA05666 |
| Clonality: | Polyclonal |
| Species Reactivity: | Human, Mouse |
| Tested Applications: | WB,IHC,ICC/IF,IP |
| Recommended Dilution: | WB: 1:2000 IHC: 1:50 ICC/IF: 1:50 IP: 1:20 |
| Size: | 30ul 50ul 100uL |
| Format: | Liquid |
| Source: | Rabbit |
| Purification Method: | Affinity Purification |
| Isotype: | IgG |
| Conjugate: | Un-conjugated |
| Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
| Immunogen: | A synthetic phosphopeptide corresponding to residues surrounding Thr45 of human eIF4EBP1 |
| Calculated Molecular Weight: | 13 kDa |
| Observed Molecular Weight: | 15-20 kDa |
| GenBank Accession Number: | Q13541 |
| Gene ID (NCBI): | 1978 |
| Synonyms: | BP-1; 4EBP1; 4E-BP1; PHAS-I |
| Background: | This gene encodes one member of a family of translation repressor proteins. The protein directly interacts with eukaryotic translation initiation factor 4E (eIF4E), which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5' end of mRNAs. Interaction of this protein with eIF4E inhibits complex assembly and represses translation. This protein is phosphorylated in response to various signals including UV irradiation and insulin signaling, resulting in its dissociation from eIF4E and activation of mRNA translation. [provided by RefSeq, Jul 2008] |
| Category: | Primary Ab |
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