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GDF15 Rabbit pAb

Cat No.: DPA05178
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Product Name: GDF15 Rabbit pAb
Cat No.: DPA05178
Clonality: Polyclonal
Species Reactivity: Human
Tested Applications: WB,IHC,IP
Recommended Dilution: WB: 1:1000
IHC: 1:20
IP: 1:20
Size: 30ul 50ul 100uL
Format: Liquid
Source: Rabbit
Purification Method: Affinity Purification
Isotype: IgG
Conjugate: Un-conjugated
Storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a
Immunogen: Recombinant protein of human GDF15
Calculated Molecular Weight: 34 kDa
Observed Molecular Weight: 35,13 kDa
GenBank Accession Number: Q99988
Gene ID (NCBI): 9518
Synonyms: PDF; MIC1; PLAB; MIC-1; NAG-1; PTGFB; GDF-15
Background: This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. The protein is expressed in a broad range of cell types, acts as a pleiotropic cytokine and is involved in the stress response program of cells after cellular injury. Increased protein levels are associated with disease states such as tissue hypoxia, inflammation, acute injury and oxidative stress. [provided by RefSeq, Aug 2016]
Category: Primary Ab
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