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分子生物学
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查看说明书Recombinant Growth Differentiation Factor 15 (GDF15)
Cat#:TP02219应用：Positive Control; Immunogen; SDS-PAGE; WB
| Product Name: | GDF15 Rabbit pAb |
| Cat No.: | DPA01081 |
| Clonality: | Polyclonal |
| Species Reactivity: | Human |
| Tested Applications: | WB |
| Recommended Dilution: | WB: 1:1000 |
| Size: | 30ul 50ul 100uL |
| Format: | Liquid |
| Source: | Rabbit |
| Purification Method: | Affinity Purification |
| Isotype: | IgG |
| Conjugate: | Un-conjugated |
| Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
| Immunogen: | A synthetic peptide of human GDF15 |
| Calculated Molecular Weight: | 34 kDa |
| Observed Molecular Weight: | 34 kDa |
| GenBank Accession Number: | Q99988 |
| Gene ID (NCBI): | 9518 |
| Synonyms: | PDF; MIC1; PLAB; MIC-1; NAG-1; PTGFB; GDF-15 |
| Background: | This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. The protein is expressed in a broad range of cell types, acts as a pleiotropic cytokine and is involved in the stress response program of cells after cellular injury. Increased protein levels are associated with disease states such as tissue hypoxia, inflammation, acute injury and oxidative stress. [provided by RefSeq, Aug 2016] |
| Category: | Primary Ab |
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