FADD Rabbit pAb
Cat#:DPA01412应用:WB,IHC,FC
Product Name: | FADD Recombinant Rabbit mAb |
Cat No.: | RMA01003 |
Clonality: | Monoclonal |
Species Reactivity: | Mouse, Rat |
Tested Applications: | WB, IHC, FC |
Recommended Dilution: | WB, IHC, FC |
Size: | 30ul 50ul 100uL |
Format: | Liquid |
Source: | Rabbit |
Purification Method: | Affinity Purification |
Isotype: | IgG |
Conjugate: | Un-conjugated |
Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
Immunogen: | A synthetic peptide of mouse FADD |
Calculated Molecular Weight: | 23 kDa |
Observed Molecular Weight: | 28 kDa |
GenBank Accession Number: | Q61160 |
Gene ID (NCBI): | 14082 |
Synonyms: | Mort1/FADD |
Background: | Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis (By similarity). Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling (By similarity). |
Category: | Primary Ab |