蛋白
抗体
检测试剂盒
蛋白MARKER
分子生物学
规格：
查看说明书FADD Rabbit pAb
Cat#:DPA01412应用：WB,IHC,FC
| Product Name: | FADD Rabbit pAb |
| Cat No.: | DPA01412 |
| Clonality: | Polyclonal |
| Species Reactivity: | Mouse |
| Tested Applications: | WB,IHC,FC |
| Recommended Dilution: | WB: 1:1000-1:5000 IHC: 1:20-1:50 FC: 1:20 |
| Size: | 30ul 50ul 100uL |
| Format: | Liquid |
| Source: | Rabbit |
| Purification Method: | Affinity Purification |
| Isotype: | IgG |
| Conjugate: | Un-conjugated |
| Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
| Immunogen: | A synthetic peptide of mouse FADD |
| Calculated Molecular Weight: | 23 kDa |
| Observed Molecular Weight: | 28 kDa |
| GenBank Accession Number: | Q61160 |
| Gene ID (NCBI): | 14082 |
| Synonyms: | Mort1/FADD |
| Background: | Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis (By similarity). Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling (By similarity). |
| Category: | Primary Ab |
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