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FADD Rabbit pAb

Cat No.: DPA01412
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Product Name: FADD Rabbit pAb
Cat No.: DPA01412
Clonality: Polyclonal
Species Reactivity: Mouse
Tested Applications: WB,IHC,FC
Recommended Dilution: WB: 1:1000-1:5000
IHC: 1:20-1:50
FC: 1:20
Size: 30ul 50ul 100uL
Format: Liquid
Source: Rabbit
Purification Method: Affinity Purification
Isotype: IgG
Conjugate: Un-conjugated
Storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a
Immunogen: A synthetic peptide of mouse FADD
Calculated Molecular Weight: 23 kDa
Observed Molecular Weight: 28 kDa
GenBank Accession Number: Q61160
Gene ID (NCBI): 14082
Synonyms: Mort1/FADD
Background: Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis (By similarity). Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling (By similarity).
Category: Primary Ab
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