Caldesmon Rabbit pAb
Cat#:DPA02153应用:WB,IHC
Product Name: | Caldesmon Recombinant Rabbit mAb |
Cat No.: | RMA01127 |
Clonality: | Monoclonal |
Species Reactivity: | Human, Mouse, Rat |
Tested Applications: | WB,IHC,ICC/IF,FC,IP |
Recommended Dilution: | WB,IHC,ICC/IF,FC,IP |
Size: | 30ul 50ul 100uL |
Format: | Liquid |
Source: | Rabbit |
Purification Method: | Affinity Purification |
Isotype: | IgG |
Conjugate: | Un-conjugated |
Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
Immunogen: | A synthetic peptide of human Caldesmon |
Calculated Molecular Weight: | 93 kDa |
Observed Molecular Weight: | 70-80 kDa |
GenBank Accession Number: | Q05682 |
Gene ID (NCBI): | 800 |
Synonyms: | CDM; HCAD; LCAD; H-CAD; L-CAD; NAG22 |
Background: | This gene encodes a calmodulin- and actin-binding protein that plays an essential role in the regulation of smooth muscle and nonmuscle contraction. The conserved domain of this protein possesses the binding activities to Ca(2+)-calmodulin, actin, tropomyosin, myosin, and phospholipids. This protein is a potent inhibitor of the actin-tropomyosin activated myosin MgATPase, and serves as a mediating factor for Ca(2+)-dependent inhibition of smooth muscle contraction. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008] |
Category: | Primary Ab |