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Phospho-Caldesmon (Thr753) Rabbit pAb

Cat No.: DPA05632
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Product Name: Phospho-Caldesmon (Thr753) Rabbit pAb
Cat No.: DPA05632
Clonality: Polyclonal
Species Reactivity: Human
Tested Applications: WB,ICC/IF
Recommended Dilution: WB: 1:1000
ICC/IF: 1:20
Size: 30ul 50ul 100uL
Format: Liquid
Source: Rabbit
Purification Method: Affinity Purification
Isotype: IgG
Conjugate: Un-conjugated
Storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a
Immunogen: A synthetic phosphopeptide corresponding to residues surrounding Thr753 of human Caldesmon
Calculated Molecular Weight: 93 kDa
Observed Molecular Weight: 80 kDa
GenBank Accession Number: Q05682
Gene ID (NCBI): 800
Synonyms: CDM; HCAD; LCAD; H-CAD; L-CAD; NAG22
Background: This gene encodes a calmodulin- and actin-binding protein that plays an essential role in the regulation of smooth muscle and nonmuscle contraction. The conserved domain of this protein possesses the binding activities to Ca(2+)-calmodulin, actin, tropomyosin, myosin, and phospholipids. This protein is a potent inhibitor of the actin-tropomyosin activated myosin MgATPase, and serves as a mediating factor for Ca(2+)-dependent inhibition of smooth muscle contraction. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008]
Category: Primary Ab
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