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PIM1 Recombinant Rabbit mAb

Cat No.: RMA01552
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Product Name: PIM1 Recombinant Rabbit mAb
Cat No.: RMA01552
Clonality: Monoclonal
Species Reactivity: Human, Mouse
Tested Applications: WB,IHC,ICC/IF,FC
Recommended Dilution: WB,IHC,ICC/IF,FC
Size: 30ul 50ul 100uL
Format: Liquid
Source: Rabbit
Purification Method: Affinity Purification
Isotype: IgG
Conjugate: Un-conjugated
Storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a
Immunogen: A synthetic peptide of human PIM1
Calculated Molecular Weight: 45 kDa
Observed Molecular Weight: 34 kDa
GenBank Accession Number: P11309
Gene ID (NCBI): 5292
Synonyms: PIM
Background: The protein encoded by this gene belongs to the Ser/Thr protein kinase family, and PIM subfamily. This gene is expressed primarily in B-lymphoid and myeloid cell lines, and is overexpressed in hematopoietic malignancies and in prostate cancer. It plays a role in signal transduction in blood cells, contributing to both cell proliferation and survival, and thus provides a selective advantage in tumorigenesis. Both the human and orthologous mouse genes have been reported to encode two isoforms (with preferential cellular localization) resulting from the use of alternative in-frame translation initiation codons, the upstream non-AUG (CUG) and downstream AUG codons (PMIDs:16186805, 1825810).[provided by RefSeq, Aug 2011]
Category: Primary Ab
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