Recombinant Pim-1 Oncogene (PIM1)
Cat#:TP03407应用:Positive Control; Immunogen; SDS-PAGE; WB
Product Name: | PIM1 Rabbit pAb |
Cat No.: | DPA03827 |
Clonality: | Polyclonal |
Species Reactivity: | Human, Mouse |
Tested Applications: | WB,IHC,ICC/IF,FC |
Recommended Dilution: | WB: 1:2000-1:10000 IHC: 1:20-1:50 ICC/IF: 1:20-1:100 FC: 1:20 |
Size: | 30ul 50ul 100uL |
Format: | Liquid |
Source: | Rabbit |
Purification Method: | Affinity Purification |
Isotype: | IgG |
Conjugate: | Un-conjugated |
Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
Immunogen: | A synthetic peptide of human PIM1 |
Calculated Molecular Weight: | 45 kDa |
Observed Molecular Weight: | 34 kDa |
GenBank Accession Number: | P11309 |
Gene ID (NCBI): | 5292 |
Synonyms: | PIM |
Background: | The protein encoded by this gene belongs to the Ser/Thr protein kinase family, and PIM subfamily. This gene is expressed primarily in B-lymphoid and myeloid cell lines, and is overexpressed in hematopoietic malignancies and in prostate cancer. It plays a role in signal transduction in blood cells, contributing to both cell proliferation and survival, and thus provides a selective advantage in tumorigenesis. Both the human and orthologous mouse genes have been reported to encode two isoforms (with preferential cellular localization) resulting from the use of alternative in-frame translation initiation codons, the upstream non-AUG (CUG) and downstream AUG codons (PMIDs:16186805, 1825810).[provided by RefSeq, Aug 2011] |
Category: | Primary Ab |