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SFT Recombinant Rabbit mAb

Cat No.: RMA02267
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  • Western blot analysis of Anti-SFT antibody(RMA02267) Gel: 15%SDS-PAGE Lysate: 20 μg Primary antibody: RMA02267(SFT antibody)at dilution 1:1000 Secondary antibody: Goat anti rabbit IgG (SPA10002)at 1:1000 dilution

Product Name: SFT Recombinant Rabbit mAb
Cat No.: RMA02267
Clonality: Monoclonal
Species Reactivity: Human, Mouse, Rat
Tested Applications: WB,IHC,FC,IP
Recommended Dilution: WB,IHC,FC,IP
Size: 30ul 50ul 100uL
Format: Liquid
Source: Rabbit
Purification Method: Affinity Purification
Isotype: IgG
Conjugate: Un-conjugated
Storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a
Immunogen: A synthetic peptide of human SFT
Calculated Molecular Weight: 17 kDa
Observed Molecular Weight: 17 kDa
GenBank Accession Number: P51668
Gene ID (NCBI): 7321
Synonyms: SFT; UBCH5; UBC4/5; UBCH5A; E2(17)KB1
Background: The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is closely related to a stimulator of iron transport (SFT), and is up-regulated in hereditary hemochromatosis. It also functions in the ubiquitination of the tumor-suppressor protein p53 and the hypoxia-inducible transcription factor HIF1alpha by interacting with the E1 ubiquitin-activating enzyme and the E3 ubiquitin-protein ligases. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2011]
Category: Primary Ab
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