Recombinant Human UBE2D1 Protein
Cat#:TP04378应用:Positive Control; Immunogen; SDS-PAGE; WB
Product Name: | SFT Recombinant Rabbit mAb |
Cat No.: | RMA02267 |
Clonality: | Monoclonal |
Species Reactivity: | Human, Mouse, Rat |
Tested Applications: | WB,IHC,FC,IP |
Recommended Dilution: | WB,IHC,FC,IP |
Size: | 30ul 50ul 100uL |
Format: | Liquid |
Source: | Rabbit |
Purification Method: | Affinity Purification |
Isotype: | IgG |
Conjugate: | Un-conjugated |
Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
Immunogen: | A synthetic peptide of human SFT |
Calculated Molecular Weight: | 17 kDa |
Observed Molecular Weight: | 17 kDa |
GenBank Accession Number: | P51668 |
Gene ID (NCBI): | 7321 |
Synonyms: | SFT; UBCH5; UBC4/5; UBCH5A; E2(17)KB1 |
Background: | The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is closely related to a stimulator of iron transport (SFT), and is up-regulated in hereditary hemochromatosis. It also functions in the ubiquitination of the tumor-suppressor protein p53 and the hypoxia-inducible transcription factor HIF1alpha by interacting with the E1 ubiquitin-activating enzyme and the E3 ubiquitin-protein ligases. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2011] |
Category: | Primary Ab |