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规格：
查看说明书Recombinant Human UBE2D1 Protein
Cat#:TP04378应用：Positive Control; Immunogen; SDS-PAGE; WB
| Product Name: | SFT Rabbit pAb |
| Cat No.: | DPA02307 |
| Clonality: | Polyclonal |
| Species Reactivity: | Human, Mouse, Rat |
| Tested Applications: | WB,IHC,FC,IP |
| Recommended Dilution: | WB: 1:2000-1:10000 IHC: 1:20 FC: 1:20 IP: 1:20 |
| Size: | 30ul 50ul 100uL |
| Format: | Liquid |
| Source: | Rabbit |
| Purification Method: | Affinity Purification |
| Isotype: | IgG |
| Conjugate: | Un-conjugated |
| Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
| Immunogen: | A synthetic peptide of human SFT |
| Calculated Molecular Weight: | 17 kDa |
| Observed Molecular Weight: | 17 kDa |
| GenBank Accession Number: | P51668 |
| Gene ID (NCBI): | 7321 |
| Synonyms: | SFT; UBCH5; UBC4/5; UBCH5A; E2(17)KB1 |
| Background: | The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is closely related to a stimulator of iron transport (SFT), and is up-regulated in hereditary hemochromatosis. It also functions in the ubiquitination of the tumor-suppressor protein p53 and the hypoxia-inducible transcription factor HIF1alpha by interacting with the E1 ubiquitin-activating enzyme and the E3 ubiquitin-protein ligases. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2011] |
| Category: | Primary Ab |
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