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分子生物学
规格：
查看说明书Recombinant Tissue Factor Pathway Inhibitor (TFPI)
Cat#:TP04185应用：Positive Control; Immunogen; SDS-PAGE; WB
| Product Name: | Tissue Factor Pathway Inhibitor Recombinant Rabbit mAb |
| Cat No.: | RMA02272 |
| Clonality: | Monoclonal |
| Species Reactivity: | Human |
| Tested Applications: | WB |
| Recommended Dilution: | WB |
| Size: | 30ul 50ul 100uL |
| Format: | Liquid |
| Source: | Rabbit |
| Purification Method: | Affinity Purification |
| Isotype: | IgG |
| Conjugate: | Un-conjugated |
| Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
| Immunogen: | A synthetic peptide of human TFPI |
| Calculated Molecular Weight: | 35 kDa |
| Observed Molecular Weight: | 40-55 kDa |
| GenBank Accession Number: | P10646 |
| Gene ID (NCBI): | 7035 |
| Synonyms: | EPI; TFI; LACI; TFPI1 |
| Background: | This gene encodes a Kunitz-type serine protease inhibitor that regulates the tissue factor (TF)-dependent pathway of blood coagulation. The coagulation process initiates with the formation of a factor VIIa-TF complex, which proteolytically activates additional proteases (factors IX and X) and ultimately leads to the formation of a fibrin clot. The product of this gene inhibits the activated factor X and VIIa-TF proteases in an autoregulatory loop. Inhibition of the encoded protein restores hemostasis in animal models of hemophilia. This gene encodes multiple protein isoforms that differ in their inhibitory activity, specificity and cellular localization. [provided by RefSeq, Jul 2016] |
| Category: | Primary Ab |
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