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TFPI Rabbit pAb

Cat No.: DPA01841
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Product Name: TFPI Rabbit pAb
Cat No.: DPA01841
Clonality: Polyclonal
Species Reactivity: Human
Tested Applications: WB,ICC/IF,IP
Recommended Dilution: WB: 1:1000
ICC/IF: 1:20
IP: 1:20
Size: 30ul 50ul 100uL
Format: Liquid
Source: Rabbit
Purification Method: Affinity Purification
Isotype: IgG
Conjugate: Un-conjugated
Storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a
Immunogen: Recombinant protein of human TFPI
Calculated Molecular Weight: 35 kDa
Observed Molecular Weight: 40-55 kDa
GenBank Accession Number: P10646
Gene ID (NCBI): 7035
Synonyms: EPI; TFI; LACI; TFPI1
Background: This gene encodes a Kunitz-type serine protease inhibitor that regulates the tissue factor (TF)-dependent pathway of blood coagulation. The coagulation process initiates with the formation of a factor VIIa-TF complex, which proteolytically activates additional proteases (factors IX and X) and ultimately leads to the formation of a fibrin clot. The product of this gene inhibits the activated factor X and VIIa-TF proteases in an autoregulatory loop. Inhibition of the encoded protein restores hemostasis in animal models of hemophilia. This gene encodes multiple protein isoforms that differ in their inhibitory activity, specificity and cellular localization. [provided by RefSeq, Jul 2016]
Category: Primary Ab
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