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Phospholipase C gamma 1 Recombinant Rabbit mAb

Cat No.: RMA02604
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  • Western blot analysis of Anti-Phospholipase C gamma 1 antibody(RMA02604) Gel: 6%SDS-PAGE Lysate: 20 μg Primary antibody: RMA02604(Phospholipase C gamma 1 antibody)at dilution 1:1000 Secondary antibody: Goat anti rabbit IgG (SPA10002)at 1:1000 dilution

Product Name: Phospholipase C gamma 1 Recombinant Rabbit mAb
Cat No.: RMA02604
Clonality: Monoclonal
Species Reactivity: Human, Mouse, Rat
Tested Applications: WB, ICC/IF, FC, IP
Recommended Dilution: WB, ICC/IF, FC, IP
Size: 30ul 50ul 100uL
Format: Liquid
Source: Rabbit
Purification Method: Affinity Purification
Isotype: IgG
Conjugate: Un-conjugated
Storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a
Immunogen: A synthetic peptide of human Phospholipase C gamma 1/PLC-gamma-1
Calculated Molecular Weight: 149 kDa
Observed Molecular Weight: 149 kDa
GenBank Accession Number: P19174
Gene ID (NCBI): 5335
Synonyms: PLC1; NCKAP3; PLC-II; PLC148; PLCgamma1
Background: The protein encoded by this gene catalyzes the formation of inositol 1,4,5-trisphosphate and diacylglycerol from phosphatidylinositol 4,5-bisphosphate. This reaction uses calcium as a cofactor and plays an important role in the intracellular transduction of receptor-mediated tyrosine kinase activators. For example, when activated by SRC, the encoded protein causes the Ras guanine nucleotide exchange factor RasGRP1 to translocate to the Golgi, where it activates Ras. Also, this protein has been shown to be a major substrate for heparin-binding growth factor 1 (acidic fibroblast growth factor)-activated tyrosine kinase. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Category: Primary Ab
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