蛋白
抗体
检测试剂盒
辅助试剂
分子生物学
规格：
查看说明书PLCG1 Rabbit pAb
Cat#:DPA01037应用：WB,ICC/IF,FC,IP
| Product Name: | PLCG1 Rabbit pAb |
| Cat No.: | DPA01037 |
| Clonality: | Polyclonal |
| Species Reactivity: | Human, Mouse, Rat |
| Tested Applications: | WB,ICC/IF,FC,IP |
| Recommended Dilution: | WB: 1:2000 ICC/IF: 1:50 FC: 1:20 IP: 1:20 |
| Size: | 30ul 50ul 100uL |
| Format: | Liquid |
| Source: | Rabbit |
| Purification Method: | Affinity Purification |
| Isotype: | IgG |
| Conjugate: | Un-conjugated |
| Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
| Immunogen: | A synthetic peptide of human Phospholipase C gamma 1/PLC-gamma-1 |
| Calculated Molecular Weight: | 149 kDa |
| Observed Molecular Weight: | 149 kDa |
| GenBank Accession Number: | P19174 |
| Gene ID (NCBI): | 5335 |
| Synonyms: | PLC1; NCKAP3; PLC-II; PLC148; PLCgamma1 |
| Background: | The protein encoded by this gene catalyzes the formation of inositol 1,4,5-trisphosphate and diacylglycerol from phosphatidylinositol 4,5-bisphosphate. This reaction uses calcium as a cofactor and plays an important role in the intracellular transduction of receptor-mediated tyrosine kinase activators. For example, when activated by SRC, the encoded protein causes the Ras guanine nucleotide exchange factor RasGRP1 to translocate to the Golgi, where it activates Ras. Also, this protein has been shown to be a major substrate for heparin-binding growth factor 1 (acidic fibroblast growth factor)-activated tyrosine kinase. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |
| Category: | Primary Ab |
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