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规格：
查看说明书TMEM173 Rabbit pAb
Cat#:DPA01174应用：WB,IHC,ICC/IF,FC
| Product Name: | Transmembrane Protein 173 Recombinant Rabbit mAb |
| Cat No.: | RMA02727 |
| Clonality: | Monoclonal |
| Species Reactivity: | Human |
| Tested Applications: | WB, IHC, ICC/IF, FC |
| Recommended Dilution: | WB, IHC, ICC/IF, FC |
| Size: | 30ul 50ul 100uL |
| Format: | Liquid |
| Source: | Rabbit |
| Purification Method: | Affinity Purification |
| Isotype: | IgG |
| Conjugate: | Un-conjugated |
| Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
| Immunogen: | Recombinant protein of human TMEM173 |
| Calculated Molecular Weight: | 42 kDa |
| Observed Molecular Weight: | 40 kDa |
| GenBank Accession Number: | Q86WV6 |
| Gene ID (NCBI): | 340061 |
| Synonyms: | ERIS; MITA; MPYS; SAVI; NET23; STING; hMITA; hSTING |
| Background: | This gene encodes a five transmembrane protein that functions as a major regulator of the innate immune response to viral and bacterial infections. The encoded protein is a pattern recognition receptor that detects cytosolic nucleic acids and transmits signals that activate type I interferon responses. The encoded protein has also been shown to play a role in apoptotic signaling by associating with type II major histocompatibility complex. Mutations in this gene are the cause of infantile-onset STING-associated vasculopathy. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2014] |
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