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TMEM173 Rabbit pAb

Cat No.: DPA01539
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Product Name: TMEM173 Rabbit pAb
Cat No.: DPA01539
Clonality: Polyclonal
Species Reactivity: Human
Tested Applications: WB,IHC,ICC/IF,FC,IP
Recommended Dilution: WB: 1:1000
IHC: 1:500
ICC/IF: 1:20
FC: 1:50
IP: 1:50
Size: 30ul 50ul 100uL
Format: Liquid
Source: Rabbit
Purification Method: Affinity Purification
Isotype: IgG
Conjugate: Un-conjugated
Storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a
Immunogen: Recombinant protein of human TMEM173
Calculated Molecular Weight: 42 kDa
Observed Molecular Weight: 40 kDa
GenBank Accession Number: Q86WV6
Gene ID (NCBI): 340061
Synonyms: ERIS; MITA; MPYS; SAVI; NET23; STING; hMITA; hSTING; TMEM173; STING-beta
Background: This gene encodes a five transmembrane protein that functions as a major regulator of the innate immune response to viral and bacterial infections. The encoded protein is a pattern recognition receptor that detects cytosolic nucleic acids and transmits signals that activate type I interferon responses. The encoded protein has also been shown to play a role in apoptotic signaling by associating with type II major histocompatibility complex. Mutations in this gene are the cause of infantile-onset STING-associated vasculopathy. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2014]
Category: Primary Ab
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