macroH2A.1 Rabbit pAb
Cat#:DPA01205应用:WB,IHC,ICC/IF
Product Name: | Macro H2A.1 Recombinant Rabbit mAb |
Cat No.: | RMA02756 |
Clonality: | Monoclonal |
Species Reactivity: | Human, Mouse, Rat |
Tested Applications: | WB, IHC, ICC/IF |
Recommended Dilution: | WB, IHC, ICC/IF |
Size: | 30ul 50ul 100uL |
Format: | Liquid |
Source: | Rabbit |
Purification Method: | Affinity Purification |
Isotype: | IgG |
Conjugate: | Un-conjugated |
Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
Immunogen: | A synthetic peptide of human macroH2A.1 |
Calculated Molecular Weight: | 40 kDa |
Observed Molecular Weight: | 40 kDa |
GenBank Accession Number: | O75367 |
Gene ID (NCBI): | 9555 |
Synonyms: | H2A.y; H2A/y; mH2A1; H2AF12M; MACROH2A1.1; macroH2A1.2 |
Background: | Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene encodes a replication-independent histone that is a member of the histone H2A family. It replaces conventional H2A histones in a subset of nucleosomes where it represses transcription and participates in stable X chromosome inactivation. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Oct 2015] |
Category: | Primary Ab |