蛋白
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检测试剂盒
蛋白MARKER
分子生物学
规格：
查看说明书macroH2A.1 Rabbit pAb
Cat#:DPA01205应用：WB,IHC,ICC/IF
| Product Name: | macroH2A.1 Rabbit pAb |
| Cat No.: | DPA01205 |
| Clonality: | Polyclonal |
| Species Reactivity: | Human, Mouse, Rat |
| Tested Applications: | WB,IHC,ICC/IF |
| Recommended Dilution: | WB: 1:2000-1:10000 IHC: 1:20-1:50 ICC/IF: 1:50 |
| Size: | 30ul 50ul 100uL |
| Format: | Liquid |
| Source: | Rabbit |
| Purification Method: | Affinity Purification |
| Isotype: | IgG |
| Conjugate: | Un-conjugated |
| Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
| Immunogen: | A synthetic peptide of human macroH2A.1 |
| Calculated Molecular Weight: | 40 kDa |
| Observed Molecular Weight: | 40 kDa |
| GenBank Accession Number: | O75367 |
| Gene ID (NCBI): | 9555 |
| Synonyms: | H2A.y; H2A/y; mH2A1; H2AF12M; MACROH2A1.1; macroH2A1.2 |
| Background: | Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene encodes a replication-independent histone that is a member of the histone H2A family. It replaces conventional H2A histones in a subset of nucleosomes where it represses transcription and participates in stable X chromosome inactivation. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Oct 2015] |
| Category: | Primary Ab |
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