Eukaryotic Alkaline Phosphatase, Tissue-nonspecific (ALPL)
Cat#:TP05383应用:Positive Control; Immunogen; SDS-PAGE; WB
Product Name: | Alkaline Phosphatase Recombinant Rabbit mAb |
Cat No.: | RMA02833 |
Clonality: | Monoclonal |
Species Reactivity: | Human, Mouse, Rat |
Tested Applications: | WB, IHC, ICC/IF, FC, IP |
Recommended Dilution: | WB, IHC, ICC/IF, FC, IP |
Size: | 30ul 50ul 100uL |
Format: | Liquid |
Source: | Rabbit |
Purification Method: | Affinity Purification |
Isotype: | IgG |
Conjugate: | Un-conjugated |
Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
Immunogen: | A synthetic peptide of human Alkaline Phosphatase, Tissue Non-Specific |
Calculated Molecular Weight: | 57 kDa |
Observed Molecular Weight: | 80 kDa |
GenBank Accession Number: | P05186 |
Gene ID (NCBI): | 249 |
Synonyms: | HOPS; TNAP; APTNAP; TNSALP; AP-TNAP |
Background: | This gene encodes a member of the alkaline phosphatase family of proteins. There are at least four distinct but related alkaline phosphatases: intestinal, placental, placental-like, and liver/bone/kidney (tissue non-specific). The first three are located together on chromosome 2, while the tissue non-specific form is located on chromosome 1. The product of this gene is a membrane bound glycosylated enzyme that is not expressed in any particular tissue and is, therefore, referred to as the tissue-nonspecific form of the enzyme. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature enzyme. This enzyme may play a role in bone mineralization. Mutations in this gene have been linked to hypophosphatasia, a disorder that is characterized by hypercalcemia and skeletal defects. [provided by RefSeq, Oct 2015] |
Category: | Primary Ab |