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Alkaline Phosphatase, Tissue Non-Specific Rabbit pAb

Cat No.: DPA01297
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Product Name: Alkaline Phosphatase, Tissue Non-Specific Rabbit pAb
Cat No.: DPA01297
Clonality: Polyclonal
Species Reactivity: Human, Mouse, Rat
Tested Applications: WB,IHC,ICC/IF,FC,IP
Recommended Dilution: WB: 1:2000-1:10000
IHC: 1:50-1:200
ICC/IF: 1:20-1:100
FC: 1:100
IP: 1:20-1:50
Size: 30ul 50ul 100uL
Format: Liquid
Source: Rabbit
Purification Method: Affinity Purification
Isotype: IgG
Conjugate: Un-conjugated
Storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a
Immunogen: A synthetic peptide of human Alkaline Phosphatase, Tissue Non-Specific
Calculated Molecular Weight: 57 kDa
Observed Molecular Weight: 80 kDa
GenBank Accession Number: P05186
Gene ID (NCBI): 249
Synonyms: HOPS; TNAP; APTNAP; TNSALP; AP-TNAP
Background: This gene encodes a member of the alkaline phosphatase family of proteins. There are at least four distinct but related alkaline phosphatases: intestinal, placental, placental-like, and liver/bone/kidney (tissue non-specific). The first three are located together on chromosome 2, while the tissue non-specific form is located on chromosome 1. The product of this gene is a membrane bound glycosylated enzyme that is not expressed in any particular tissue and is, therefore, referred to as the tissue-nonspecific form of the enzyme. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature enzyme. This enzyme may play a role in bone mineralization. Mutations in this gene have been linked to hypophosphatasia, a disorder that is characterized by hypercalcemia and skeletal defects. [provided by RefSeq, Oct 2015]
Category: Primary Ab
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