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查看说明书Recombinant Human Growth hormone receptor Protein
Cat#:TP02336应用：Positive Control; Immunogen; SDS-PAGE; WB
| Product Name: | Growth Hormone Receptor Recombinant Rabbit mAb |
| Cat No.: | RMA02879 |
| Clonality: | Monoclonal |
| Species Reactivity: | Human, Mouse, Rat |
| Tested Applications: | WB, FC, IP |
| Recommended Dilution: | WB, FC, IP |
| Size: | 30ul 50ul 100uL |
| Format: | Liquid |
| Source: | Rabbit |
| Purification Method: | Affinity Purification |
| Isotype: | IgG |
| Conjugate: | Un-conjugated |
| Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
| Immunogen: | A synthetic peptide of human Growth hormone receptor |
| Calculated Molecular Weight: | 72 kDa |
| Observed Molecular Weight: | 120 kDa |
| GenBank Accession Number: | P10912 |
| Gene ID (NCBI): | 2690 |
| Synonyms: | GHBP; GHIP |
| Background: | This gene encodes a member of the type I cytokine receptor family, which is a transmembrane receptor for growth hormone. Binding of growth hormone to the receptor leads to receptor dimerization and the activation of an intra- and intercellular signal transduction pathway leading to growth. Mutations in this gene have been associated with Laron syndrome, also known as the growth hormone insensitivity syndrome (GHIS), a disorder characterized by short stature. In humans and rabbits, but not rodents, growth hormone binding protein (GHBP) is generated by proteolytic cleavage of the extracellular ligand-binding domain from the mature growth hormone receptor protein. Multiple alternatively spliced transcript variants have been found for this gene.[provided by RefSeq, Jun 2011] |
| Category: | Primary Ab |
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