Recombinant Human Growth hormone receptor Protein
Cat#:TP02336应用:Positive Control; Immunogen; SDS-PAGE; WB
Product Name: | Growth hormone receptor Rabbit pAb |
Cat No.: | DPA01359 |
Clonality: | Polyclonal |
Species Reactivity: | Human, Mouse, Rat |
Tested Applications: | WB,FC,IP |
Recommended Dilution: | WB: 1:1000-1:5000 FC: 1:50 IP: 1:50 |
Size: | 30ul 50ul 100uL |
Format: | Liquid |
Source: | Rabbit |
Purification Method: | Affinity Purification |
Isotype: | IgG |
Conjugate: | Un-conjugated |
Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
Immunogen: | A synthetic peptide of human Growth hormone receptor |
Calculated Molecular Weight: | 72 kDa |
Observed Molecular Weight: | 120 kDa |
GenBank Accession Number: | P10912 |
Gene ID (NCBI): | 2690 |
Synonyms: | GHBP; GHIP |
Background: | This gene encodes a member of the type I cytokine receptor family, which is a transmembrane receptor for growth hormone. Binding of growth hormone to the receptor leads to receptor dimerization and the activation of an intra- and intercellular signal transduction pathway leading to growth. Mutations in this gene have been associated with Laron syndrome, also known as the growth hormone insensitivity syndrome (GHIS), a disorder characterized by short stature. In humans and rabbits, but not rodents, growth hormone binding protein (GHBP) is generated by proteolytic cleavage of the extracellular ligand-binding domain from the mature growth hormone receptor protein. Multiple alternatively spliced transcript variants have been found for this gene.[provided by RefSeq, Jun 2011] |
Category: | Primary Ab |