MCM3 Rabbit pAb
Cat#:DPA01409应用:WB,IHC,ICC/IF,FC
Product Name: | MCM3 Recombinant Rabbit mAb |
Cat No.: | RMA02910 |
Clonality: | Monoclonal |
Species Reactivity: | Human, Mouse, Rat |
Tested Applications: | WB, IHC, ICC/IF, FC |
Recommended Dilution: | WB, IHC, ICC/IF, FC |
Size: | 30ul 50ul 100uL |
Format: | Liquid |
Source: | Rabbit |
Purification Method: | Affinity Purification |
Isotype: | IgG |
Conjugate: | Un-conjugated |
Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
Immunogen: | A synthetic peptide of human MCM3 |
Calculated Molecular Weight: | 91 kDa |
Observed Molecular Weight: | 100 kDa |
GenBank Accession Number: | P25205 |
Gene ID (NCBI): | 4172 |
Synonyms: | HCC5; P1.h; RLFB; P1-MCM3 |
Background: | The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein is a subunit of the protein complex that consists of MCM2-7. It has been shown to interact directly with MCM5/CDC46. This protein also interacts with and is acetylated by MCM3AP, a chromatin-associated acetyltransferase. The acetylation of this protein inhibits the initiation of DNA replication and cell cycle progression. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2012] |
Category: | Primary Ab |