蛋白
抗体
检测试剂盒
辅助试剂
分子生物学
规格：
查看说明书MCM3 Rabbit pAb
Cat#:DPA01409应用：WB,IHC,ICC/IF,FC
| Product Name: | MCM3 Rabbit pAb |
| Cat No.: | DPA01409 |
| Clonality: | Polyclonal |
| Species Reactivity: | Human, Mouse, Rat |
| Tested Applications: | WB,IHC,ICC/IF,FC |
| Recommended Dilution: | WB: 1:1000-1:5000 IHC: 1:20-1:100 ICC/IF: 1:20-1:50 FC: 1:20 |
| Size: | 30ul 50ul 100uL |
| Format: | Liquid |
| Source: | Rabbit |
| Purification Method: | Affinity Purification |
| Isotype: | IgG |
| Conjugate: | Un-conjugated |
| Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
| Immunogen: | A synthetic peptide of human MCM3 |
| Calculated Molecular Weight: | 91 kDa |
| Observed Molecular Weight: | 100 kDa |
| GenBank Accession Number: | P25205 |
| Gene ID (NCBI): | 4172 |
| Synonyms: | HCC5; P1.h; RLFB; P1-MCM3 |
| Background: | The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein is a subunit of the protein complex that consists of MCM2-7. It has been shown to interact directly with MCM5/CDC46. This protein also interacts with and is acetylated by MCM3AP, a chromatin-associated acetyltransferase. The acetylation of this protein inhibits the initiation of DNA replication and cell cycle progression. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2012] |
| Category: | Primary Ab |
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