蛋白
抗体
检测试剂盒
蛋白MARKER
分子生物学
规格：
查看说明书Recombinant Geminin (GMNN)
Cat#:TP02227应用：Positive Control; Immunogen; SDS-PAGE; WB
| Product Name: | Geminin Recombinant Rabbit mAb |
| Cat No.: | RMA02911 |
| Clonality: | Monoclonal |
| Species Reactivity: | Human |
| Tested Applications: | WB, IHC, ICC/IF |
| Recommended Dilution: | WB, IHC, ICC/IF |
| Size: | 30ul 50ul 100uL |
| Format: | Liquid |
| Source: | Rabbit |
| Purification Method: | Affinity Purification |
| Isotype: | IgG |
| Conjugate: | Un-conjugated |
| Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
| Immunogen: | Recombinant protein of human Geminin |
| Calculated Molecular Weight: | 24 kDa |
| Observed Molecular Weight: | 24 kDa |
| GenBank Accession Number: | O75496 |
| Gene ID (NCBI): | 51053 |
| Synonyms: | Gem; MGORS6 |
| Background: | This gene encodes a protein that plays a critical role in cell cycle regulation. The encoded protein inhibits DNA replication by binding to DNA replication factor Cdt1, preventing the incorporation of minichromosome maintenance proteins into the pre-replication complex. The encoded protein is expressed during the S and G2 phases of the cell cycle and is degraded by the anaphase-promoting complex during the metaphase-anaphase transition. Increased expression of this gene may play a role in several malignancies including colon, rectal and breast cancer. Alternatively spliced transcript variants have been observed for this gene, and two pseudogenes of this gene are located on the short arm of chromosome 16. [provided by RefSeq, Oct 2011] |
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