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Geminin Rabbit pAb

Cat No.: DPA01410
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Product Name: Geminin Rabbit pAb
Cat No.: DPA01410
Clonality: Polyclonal
Species Reactivity: Human
Tested Applications: WB,IHC,ICC/IF
Recommended Dilution: WB: 1:1000
IHC: 1:50
ICC/IF: 1:20
Size: 30ul 50ul 100uL
Format: Liquid
Source: Rabbit
Purification Method: Affinity Purification
Isotype: IgG
Conjugate: Un-conjugated
Storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a
Immunogen: Recombinant protein of human Geminin
Calculated Molecular Weight: 24 kDa
Observed Molecular Weight: 24 kDa
GenBank Accession Number: O75496
Gene ID (NCBI): 51053
Synonyms: Gem; MGORS6
Background: This gene encodes a protein that plays a critical role in cell cycle regulation. The encoded protein inhibits DNA replication by binding to DNA replication factor Cdt1, preventing the incorporation of minichromosome maintenance proteins into the pre-replication complex. The encoded protein is expressed during the S and G2 phases of the cell cycle and is degraded by the anaphase-promoting complex during the metaphase-anaphase transition. Increased expression of this gene may play a role in several malignancies including colon, rectal and breast cancer. Alternatively spliced transcript variants have been observed for this gene, and two pseudogenes of this gene are located on the short arm of chromosome 16. [provided by RefSeq, Oct 2011]
Category: Primary Ab
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