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Phospho-eIF4E (Ser209) Rabbit pAb

Cat No.: DPA05324
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Product Name: Phospho-eIF4E (Ser209) Rabbit pAb
Cat No.: DPA05324
Clonality: Polyclonal
Species Reactivity: Human, Mouse, Rat
Tested Applications: WB,IHC,ICC/IF,IP
Recommended Dilution: WB: 1:1000-1:10000
IHC: 1:50
ICC/IF: 1:100
IP: 1:20
Size: 30ul 50ul 100uL
Format: Liquid
Source: Rabbit
Purification Method: Affinity Purification
Isotype: IgG
Conjugate: Un-conjugated
Storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a
Immunogen: A synthetic phosphopeptide corresponding to residues surrounding Ser209 of human eIF4E
Calculated Molecular Weight: 25 kDa
Observed Molecular Weight: 25 kDa
GenBank Accession Number: P06730
Gene ID (NCBI): 1977
Synonyms: CBP; EIF4F; AUTS19; EIF4E1; eIF-4E; EIF4EL1
Background: The protein encoded by this gene is a component of the eukaryotic translation initiation factor 4F complex, which recognizes the 7-methylguanosine cap structure at the 5' end of messenger RNAs. The encoded protein aids in translation initiation by recruiting ribosomes to the 5'-cap structure. Association of this protein with the 4F complex is the rate-limiting step in translation initiation. This gene acts as a proto-oncogene, and its expression and activation is associated with transformation and tumorigenesis. Several pseudogenes of this gene are found on other chromosomes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015]
Category: Primary Ab
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