Recombinant Human EIF4E Protein
Cat#:TP01999应用:Positive Control; Immunogen; SDS-PAGE; WB
Product Name: | Phospho-eIF4E (Ser209) Recombinant Rabbit mAb |
Cat No.: | RMA03068 |
Clonality: | Monoclonal |
Species Reactivity: | Human, Mouse, Rat |
Tested Applications: | WB, IHC, ICC/IF, IP |
Recommended Dilution: | WB: 1:1000-1:10000 IHC: 1:50 ICC/IF: 1:100 IP: 1:20 |
Size: | 30ul 50ul 100uL |
Format: | Liquid |
Source: | Rabbit |
Purification Method: | Affinity Purification |
Isotype: | IgG |
Conjugate: | Un-conjugated |
Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
Immunogen: | A synthetic phosphopeptide corresponding to residues surrounding Ser209 of human eIF4E |
Calculated Molecular Weight: | 25 kDa |
Observed Molecular Weight: | 25 kDa |
GenBank Accession Number: | P06730 |
Gene ID (NCBI): | 1977 |
Synonyms: | CBP; EIF4F; AUTS19; EIF4E1; eIF-4E; EIF4EL1 |
Background: | The protein encoded by this gene is a component of the eukaryotic translation initiation factor 4F complex, which recognizes the 7-methylguanosine cap structure at the 5' end of messenger RNAs. The encoded protein aids in translation initiation by recruiting ribosomes to the 5'-cap structure. Association of this protein with the 4F complex is the rate-limiting step in translation initiation. This gene acts as a proto-oncogene, and its expression and activation is associated with transformation and tumorigenesis. Several pseudogenes of this gene are found on other chromosomes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015] |
Category: | Primary Ab |