GCN2 Rabbit pAb
Cat#:DPA05158应用:WB,IHC,ICC/IF,FC
Product Name: | Phospho-GCN2 (Thr667) Rabbit pAb |
Cat No.: | DPA05345 |
Clonality: | Polyclonal |
Species Reactivity: | Human |
Tested Applications: | WB,IP |
Recommended Dilution: | WB: 1:1000 IP: 1:20 |
Size: | 30ul 50ul 100uL |
Format: | Liquid |
Source: | Rabbit |
Purification Method: | Affinity Purification |
Isotype: | IgG |
Conjugate: | Un-conjugated |
Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
Immunogen: | A synthetic phosphopeptide corresponding to residues surrounding Thr667 of human GCN2 |
Calculated Molecular Weight: | 187 kDa |
Observed Molecular Weight: | 220 kDa |
GenBank Accession Number: | Q9P2K8 |
Gene ID (NCBI): | 440275 |
Synonyms: | GCN2; PVOD2 |
Background: | This gene encodes a member of a family of kinases that phosphorylate the alpha subunit of eukaryotic translation initiation factor-2 (EIF2), resulting in the downregulaton of protein synthesis. The encoded protein responds to amino acid deprivation by binding uncharged transfer RNAs. It may also be activated by glucose deprivation and viral infection. Mutations in this gene have been found in individuals suffering from autosomal recessive pulmonary venoocclusive-disease-2. [provided by RefSeq, Mar 2014] |
Category: | Primary Ab |