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Phospho-GCN2 (Thr899) Rabbit pAb

Cat No.: DPA05488
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Product Name: Phospho-GCN2 (Thr899) Rabbit pAb
Cat No.: DPA05488
Clonality: Polyclonal
Species Reactivity: Human
Tested Applications: WB
Recommended Dilution: WB: 1:1000
Size: 30ul 50ul 100uL
Format: Liquid
Source: Rabbit
Purification Method: Affinity Purification
Isotype: IgG
Conjugate: Un-conjugated
Storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a
Immunogen: A synthetic phosphopeptide corresponding to residues surrounding Thr899 of human GCN2
Calculated Molecular Weight: 187 kDa
Observed Molecular Weight: 220 kDa
GenBank Accession Number: Q9P2K8
Gene ID (NCBI): 440275
Synonyms: GCN2; PVOD2
Background: This gene encodes a member of a family of kinases that phosphorylate the alpha subunit of eukaryotic translation initiation factor-2 (EIF2), resulting in the downregulaton of protein synthesis. The encoded protein responds to amino acid deprivation by binding uncharged transfer RNAs. It may also be activated by glucose deprivation and viral infection. Mutations in this gene have been found in individuals suffering from autosomal recessive pulmonary venoocclusive-disease-2. [provided by RefSeq, Mar 2014]
Category: Primary Ab
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