AMPK alpha 2 Rabbit pAb
Cat#:DPA03910应用:WB,IP
Product Name: | Phospho-AMPK alpha 1 (Thr183)/AMPK alpha 2 (Thr172) Rabbit pAb |
Cat No.: | DPA05516 |
Clonality: | Polyclonal |
Species Reactivity: | Human, Mouse, Rat |
Tested Applications: | WB |
Recommended Dilution: | WB: 1:1000 |
Size: | 30ul 50ul 100uL |
Format: | Liquid |
Source: | Rabbit |
Purification Method: | Affinity Purification |
Isotype: | IgG |
Conjugate: | Un-conjugated |
Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
Immunogen: | A synthetic phosphopeptide corresponding to residues surrounding Thr183/Thr172 of human AMPK alpha 1 |
Calculated Molecular Weight: | 64,62 kDa |
Observed Molecular Weight: | 62 kDa |
GenBank Accession Number: | P54646 |
Gene ID (NCBI): | 5562 |
Synonyms: | AMPK; AMPKa1 |
Background: | The protein encoded by this gene belongs to the ser/thr protein kinase family. It is the catalytic subunit of the 5'-prime-AMP-activated protein kinase (AMPK). AMPK is a cellular energy sensor conserved in all eukaryotic cells. The kinase activity of AMPK is activated by the stimuli that increase the cellular AMP/ATP ratio. AMPK regulates the activities of a number of key metabolic enzymes through phosphorylation. It protects cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways. Alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jul 2008] |
Category: | Primary Ab |