蛋白
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检测试剂盒
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分子生物学
规格：
查看说明书ULK1 Rabbit pAb
Cat#:DPA03224应用：WB
| Product Name: | Phospho-ULK1 (Ser467) Rabbit pAb |
| Cat No.: | DPA05526 |
| Clonality: | Polyclonal |
| Species Reactivity: | Human |
| Tested Applications: | WB |
| Recommended Dilution: | WB: 1:1000 |
| Size: | 30ul 50ul 100uL |
| Format: | Liquid |
| Source: | Rabbit |
| Purification Method: | Affinity Purification |
| Isotype: | IgG |
| Conjugate: | Un-conjugated |
| Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
| Immunogen: | A synthetic phosphopeptide corresponding to residues surrounding Ser467 of human ULK1 |
| Calculated Molecular Weight: | 113 kDa |
| Observed Molecular Weight: | 130 kDa |
| GenBank Accession Number: | O75385 |
| Gene ID (NCBI): | 8408 |
| Synonyms: | ATG1; ATG1A; UNC51; hATG1; Unc51.1 |
| Background: | Serine/threonine-protein kinase involved in autophagy in response to starvation. Acts upstream of phosphatidylinositol 3-kinase PIK3C3 to regulate the formation of autophagophores, the precursors of autophagosomes. Part of regulatory feedback loops in autophagy: acts both as a downstream effector and negative regulator of mammalian target of rapamycin complex 1 (mTORC1) via interaction with RPTOR. |
| Category: | Primary Ab |
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