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规格：
查看说明书Recombinant Linker For Activation Of T-Cell (LAT)
Cat#:TP02782应用：Positive Control; Immunogen; SDS-PAGE; WB
| Product Name: | Phospho-LAT (Tyr200) Rabbit pAb |
| Cat No.: | DPA05672 |
| Clonality: | Polyclonal |
| Species Reactivity: | Human |
| Tested Applications: | WB,ICC/IF |
| Recommended Dilution: | WB: 1:2000 ICC/IF: 1:50 |
| Size: | 30ul 50ul 100uL |
| Format: | Liquid |
| Source: | Rabbit |
| Purification Method: | Affinity Purification |
| Isotype: | IgG |
| Conjugate: | Un-conjugated |
| Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
| Immunogen: | A synthetic phosphopeptide corresponding to residues surrounding Tyr200 of human LAT |
| Calculated Molecular Weight: | 28 kDa |
| Observed Molecular Weight: | 36-38 kDa |
| GenBank Accession Number: | O43561 |
| Gene ID (NCBI): | 27040 |
| Synonyms: | LAT1; pp36; IMD52 |
| Background: | The protein encoded by this gene is phosphorylated by ZAP-70/Syk protein tyrosine kinases following activation of the T-cell antigen receptor (TCR) signal transduction pathway. This transmembrane protein localizes to lipid rafts and acts as a docking site for SH2 domain-containing proteins. Upon phosphorylation, this protein recruits multiple adaptor proteins and downstream signaling molecules into multimolecular signaling complexes located near the site of TCR engagement. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008] |
| Category: | Primary Ab |
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