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LAT Rabbit pAb

Cat No.: DPA04293
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Product Name: LAT Rabbit pAb
Cat No.: DPA04293
Clonality: Polyclonal
Species Reactivity: Human
Tested Applications: WB,IHC,FC,IP
Recommended Dilution: WB: 1:1000
IHC: 1:20
FC: 1:20
IP: 1:20
Size: 30ul 50ul 100uL
Format: Liquid
Source: Rabbit
Purification Method: Affinity Purification
Isotype: IgG
Conjugate: Un-conjugated
Storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a
Immunogen: A synthetic peptide of human LAT
Calculated Molecular Weight: 28 kDa
Observed Molecular Weight: 36 kDa
GenBank Accession Number: O43561
Gene ID (NCBI): 27040
Synonyms: LAT1; pp36; IMD52
Background: The protein encoded by this gene is phosphorylated by ZAP-70/Syk protein tyrosine kinases following activation of the T-cell antigen receptor (TCR) signal transduction pathway. This transmembrane protein localizes to lipid rafts and acts as a docking site for SH2 domain-containing proteins. Upon phosphorylation, this protein recruits multiple adaptor proteins and downstream signaling molecules into multimolecular signaling complexes located near the site of TCR engagement. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
Category: Primary Ab
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